1. 玩弄,轻视,不严肃对待：touch up修饰,改进 | trifle with玩弄,轻视,不严肃对待 | turn about转身,掉转;改变看法(意见),反复思考
2. 视同儿戏：trifle away 浪费 | trifle with 视同儿戏 | trifle 琐事
3. 愚弄,忽略：734.too much to say 过言. | 735.trifle with 愚弄,忽略. | 736.true to 对...守节,忠于.
4. 玩忽,嬉耍：1091. lose track 失去联系 | 1092. trifle with 玩忽,嬉耍 | 1093. trust in 信任,依赖
1. (不能)轻慢;(不可）小看;(不可)怠慢
If you say that someone is not a person to be trifled with, you are indicating to other people that they must treat that person with respect.
e.g. He was not someone to be trifled with...
对他可不能小觑。
e.g. No man in Tabriz trifled with the executioner.
在大不里士没人敢轻视行刑者。